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Antibodies

Volume 2: Novel Technologies And Therapeutic Use

Antibodies - Subramanian, G. - ISBN: 9780306483158
Prijs: € 163,80
Levertijd: 12 tot 15 werkdagen
Bindwijze: Boek, Gebonden
Genre: Biomedische technologie
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Beschrijving

Both The Nature Of Monoclonal Antibody Therapies And The Relatively Large Size Of The Monoclonal Antibody Dictate The Production Requirements, For Many Ofthese Therapeutics The Monoclonal Antibody Product Will Be 100 Kilogrammes Or More Per Year.

Details

Titel: Antibodies
auteur: Subramanian, G.
Mediatype: Boek
Bindwijze: Gebonden
Taal: Engels
Aantal pagina's: 232
Uitgever: Springer Science+business Media
Plaats van publicatie: 01
NUR: Biomedische technologie
Afmetingen: 235 x 155
Gewicht: 593 gr
ISBN/ISBN13: 0306483157
ISBN/ISBN13: 9780306483158
Intern nummer: 2108216
Volume: 2

Extra informatie

Volume 2: Novel Technologies and Therapeutic Use brings to the forefront current advances in novel technologies for the manufacturing of monoclonal antibodies and also their extensive clinical importance. Following on from Antibodies Volume 1: Production and Purification, this volume concentrates on: -new technologies in the manufacture of monoclonal antibodies, -the application of antibodies in cancer therapy and functional genomic therapy, -the importance of antibodies and prospects of antibody engineering for the future.

Inhoudsopgave

Volume 1:- 1. Concepts in Development of Manufacturing Strategies for Monoclonal Antibodies; B. Fish. 2. Antibody Fragments: Production, Purification and Formatting for Therapeutic Applications; D.J. Glover, D.P. Humphreys. 3. Large Scale Production of Therapeutic Antibodies: Considerations for Optimizing Product Capture and Purification; G. Kemp, P. O'Neil. 4. Scale-Up of Antibody Purification. From Laboratory Scale to Production; L.R. Jacob, M. Frech. 5. Purification of Antibody by Chromatographic Methods; C. Vandevyver, R. Freitag. 6. Quality Control of Antibodies for Human Use; A. Richter, M. Jostameling, K. Müller, A. Herrmann, M. Pitschke. 7. Expression of Human Anti Rh(D) Monoclonal Antibodies into Different Cell lines: Influence on their Functional Properties; C. de Romeuf, C. Gaucher, A. Glacet, S. Jorieux, P. Klein, D. Bourel. 8. Monoclonal Antibody Production: Minimising Virus Safety Issues; J. Bray, M.K. Brattle. 9. Contract Manufacturing of Biopharmaceutical Grade Antibodies; L.A. Van Der Pol, D.F. Westra. 10. The Pharmacokinetics and Pharmacodynamics of Monoclonal Antibodies; D.B. Haughey, P.M. Jardieu. 11. Regulatory and Legal Requirements for the Manufacture of Antibodies; L. Tsang. Index. Volume 2:- 1. Transgenic technology for monoclonal antibody production; S. Sensoli. 2. Generation, engineering and production of human antibodies using HuCAL; R. Ostendorp, C. Frisch, M. Urban. 3. Achieving appropriate glycosylation during the scaleup of antibody production; X.K. Deng, T. Shantha Raju, K.J. Morrow Jr. 4. Approaches to devise antibody purification processes by chromatography; E. Boschetti. 5. Novel HIV neutralizing antibodies selected from phage display libraries; M. Moulard, Mei-Yun Zhang, D.S. Dimitrov. 6. Monoclonal and bispecific antibodies in combination with radiotherapy for cancer treatment; D. Azria, C. Larbouret, B. Robert, M. Ozsahin, J.B. Dubois, A. Pèlegrin. 7. Antibodies, a potent tool to target genes into designated cells and tissues; F. Hirsch, O. Deas, G. Carvalho, A. Dürrbach, D. Thierry, A. Chapel. 8. Intrabodies: development and application in functional genomics and therapy; A. Barberis, A. Auf Der Maur, K. Tissot, P. Lichtlen. 9. Expression of recombinant antibodies by tumour cells: on road to anti-tumour therapy; E. Bonnin, J.-L. Teillaud. 10. Antitumor antibodies: from research to clinic; S. Ménard, S.M. Pupa, M. Campiglio, E. Tagliabue. 11. Macrophages for immunotherapy; D. Loirat, S. Jacod, A. Boyer, F. Auzelle, A. McAllister, J.-P. Abstado, J. Bartholeyns, D. Prigent. 12. Future prospects in antibody engineering and therapy; S. Siberil, J.-L. Teillaud. Index.

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